Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.51 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SMO | Q99835 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2666990 | 0.77 | MAOA (0.50) | MEN1KMT2APOLBMAOAMAOB | |
| SCHEMBL9072004 | 0.71 | MAOA (0.51) | RAB9ANPC1MEN1KMT2AMAOA | |
| SCHEMBL2667043 | 0.70 | CXCL12 (0.60) | MEN1KMT2AMAOAMAOBMAPT | |
| SCHEMBL2666743 | 0.70 | PKM (0.41) | MEN1KMT2APOLBMAOAMAOB | |
| SCHEMBL1528674 | 0.69 | BCHE (0.64) | KCNK9KCNK3RAB9ANPC1NLRP3 | |
| SCHEMBL2176828 | 0.68 | NPC1 (1.00) | KCNK9KCNK3RAB9ANPC1NLRP3 | |
| SCHEMBL29800540 | 0.68 | NPC1 (1.00) | KCNK9KCNK3RAB9ANPC1NLRP3 | |
| SCHEMBL20227586 | 0.67 | KCNK3 (0.79) | KCNK9KCNK3RAB9ANPC1TRPV1 | |
| SCHEMBL2666926 | 0.67 | MAOA (0.44) | RAB9AMEN1KMT2APOLBMAOA | |
| SCHEMBL4253111 | 0.66 | TRPV1 (1.00) | KCNK9KCNK3RAB9ANPC1NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007061923-A2 | GLUCOKINASE ACTIVATORS | TAKEDA SAN DIEGO, INC. (US) | 2007-05-31 | — | — | WO | disclosed |