Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 2/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | TEK | Q02763 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24936306 | 0.85 | MAPT (0.35) | — | |
| SCHEMBL29827219 | 0.80 | KCNH2 (0.52) | KCNH2AXL | |
| SCHEMBL24936185 | 0.80 | KCNH2 (0.52) | KCNH2AXL | |
| SCHEMBL26668640 | 0.79 | — | — | |
| SCHEMBL18955276 | 0.78 | CYP1A2 (0.43) | HPGDHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL26668645 | 0.77 | ALDH1A1 (0.35) | KCNH2CHEK1TRPV1AURKALCK | |
| SCHEMBL29045194 | 0.73 | CYP1A2 (0.35) | CHEK1 | |
| SCHEMBL29045183 | 0.69 | MTNR1A (0.41) | KCNH2AURKALCKKDRTEK | |
| SCHEMBL24936246 | 0.69 | KCNH2 (0.43) | KCNH2AXL | |
| SCHEMBL19007376 | 0.68 | DRD2 (0.45) | KCNH2AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023229032-A1 | THERAPEUTIC FOR CANCER REFRACTORY TO IMMUNE CHECKPOINT INHIBITOR | 住友ファーマ株式会社 | 2023-11-30 | — | — | WO | disclosed |