Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | GCK | P35557 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667639 | 0.87 | HTT (0.38) | LMNAALDH1A1GAASMN1; SMN2MAPT | |
| SCHEMBL2667602 | 0.87 | SMN1; SMN2 (0.59) | LMNAALDH1A1GAASMN1; SMN2BRD4 | |
| SCHEMBL2667500 | 0.81 | L3MBTL1 (0.46) | LMNAALDH1A1GAASMN1; SMN2BRD4 | |
| SCHEMBL2667935 | 0.81 | RAB9A (0.43) | LMNAALDH1A1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL9070806 | 0.81 | RAB9A (0.43) | LMNAALDH1A1GAASMN1; SMN2RAB9A | |
| SCHEMBL9070922 | 0.79 | GCK (0.43) | LMNAALDH1A1GAASMN1; SMN2RAB9A | |
| SCHEMBL9070824 | 0.78 | SMN1; SMN2 (0.44) | LMNAALDH1A1GAASMN1; SMN2RAB9A | |
| SCHEMBL13927363 | 0.77 | ALDH1A1 (0.43) | LMNAALDH1A1SMN1; SMN2BRD4MAPT | |
| SCHEMBL9070981 | 0.77 | KDM4E (0.35) | LMNAALDH1A1GAASMN1; SMN2MAPT | |
| SCHEMBL9070999 | 0.76 | RAB9A (0.63) | LMNAALDH1A1GAASMN1; SMN2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |