Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA3 | P15088 | 3/20 | 0.77 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CPA1 | P15085 | 2/20 | 0.61 |
| ▸ | CPB1 | P15086 | 1/20 | 0.61 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.61 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28430963 | 0.98 | CPA3 (0.75) | CPA3FOLH1CYP1A2CPA1CPB1 | |
| SCHEMBL31303730 | 0.98 | CPA3 (0.75) | CPA3FOLH1CYP1A2CPA1CPB1 | |
| SCHEMBL11143841 | 0.98 | CPA3 (0.75) | CPA3FOLH1CYP1A2CPA1CPB1 | |
| SCHEMBL28600681 | 0.98 | CPA3 (0.75) | CPA3FOLH1CYP1A2CPA1CPB1 | |
| SCHEMBL3174797 | 0.95 | CPA3 (0.80) | CPA3FOLH1CYP1A2CPA1CPB1 | |
| SCHEMBL12494537 | 0.95 | CPA3 (0.80) | CPA3FOLH1CYP1A2CPA1CPB1 | |
| SCHEMBL3963424 | 0.87 | CPA3 (1.00) | CPA3FOLH1CYP1A2CPA1CPB1 | |
| SCHEMBL29088272 | 0.87 | CPA3 (1.00) | CPA3FOLH1CYP1A2CPA1CPB1 | |
| SCHEMBL11664393 | 0.87 | FOLH1 (0.79) | CPA3FOLH1CYP1A2CPA1CPB1 | |
| SCHEMBL11074746 | 0.85 | CPA3 (0.57) | CPA3FOLH1CYP1A2CPA1CPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250326731-A1 | CATALYST-CONTROLLED SITE-SELECTIVE METHYLENE C-H LACTONIZATION OF DICARBOXYLIC ACIDS | SCRIPPS RESEARCH INST (US) | 2025-10-23 | — | — | US | disclosed |
| EP-4522595-A2 | CATALYST-CONTROLLED SITE-SELECTIVE METHYLENE C-H LACTONIZATION OF DICARBOXYLIC ACIDS | The Scripps Research Institute (US) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023220559-A2 | CATALYST-CONTROLLED SITE-SELECTIVE METHYLENE C-H LACTONIZATION OF DICARBOXYLIC ACIDS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023220559-A2 | CATALYST-CONTROLLED SITE-SELECTIVE METHYLENE C-H LACTONIZATION OF DICARBOXYLIC ACIDS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-11-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250326731-A1 | CATALYST-CONTROLLED SITE-SELECTIVE METHYLENE C-H LACTONIZATION OF DICARBOXYLIC ACIDS | DNPH1, NISCH, PTMA | CPA3 394/4885FOLH1 150/4885CYP1A2 3500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.