SCHEMBL3963424

SCHEMBL3963424

O=C(O)CCC(Cc1ccccc1)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CPA3 P15088 3/20 1.00
CYP1A2 P05177 1/20 0.70
CPA1 P15085 2/20 0.67
CPB1 P15086 1/20 0.67
CPB2 Q96IY4 1/20 0.67
FOLH1 Q04609 2/20 0.64
NAALAD2 Q9Y3Q0 2/20 0.61
SLC1A3 P43003 1/20 0.56
SLC1A2 P43004 1/20 0.56
SLC1A1 P43005 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29088272 1.00 CPA3 (1.00) CPA3CYP1A2CPA1CPB1CPB2
SCHEMBL17537902 0.92 CPA3 (0.85) CPA3CYP1A2CPA1CPB1CPB2
SCHEMBL3174797 0.89 CPA3 (0.80) CPA3CYP1A2CPA1CPB1CPB2
SCHEMBL12494537 0.89 CPA3 (0.80) CPA3CYP1A2CPA1CPB1CPB2
SCHEMBL12494233 0.88 CYP1A2 (0.83) CPA3CYP1A2CPA1CPB1CPB2
SCHEMBL19821208 0.88 CYP1A2 (0.83) CPA3CYP1A2CPA1CPB1CPB2
SCHEMBL6724759 0.88 CYP1A2 (0.83) CPA3CYP1A2CPA1CPB1CPB2
SCHEMBL26679347 0.87 CPA3 (0.77) CPA3CYP1A2CPA1CPB1CPB2
SCHEMBL11143841 0.86 CPA3 (0.75) CPA3CYP1A2CPA1CPB1CPB2
SCHEMBL31303730 0.86 CPA3 (0.75) CPA3CYP1A2CPA1CPB1CPB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115570263-A Laser control structure and laser bonding method using the same 韩国电子通信研究院 2023-01-06 CN claimed
US-20220402070-A1 LASER CONTROL STRUCTURE AND LASER BONDING METHOD USING THE SAME ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2022-12-22 US claimed
EP-4534092-B1 COMPOSITIONS AND METHODS FOR MODULATING PKK EXPRESSION IONIS PHARMACEUTICALS INC (US) 2026-04-15 EP disclosed
EP-4711459-A2 CONJUGATED ANTISENSE COMPOUNDS AND THEIR USE Ionis Pharmaceuticals, Inc. (US) 2026-03-18 EP disclosed
US-20260035695-A1 COMPOSITIONS AND METHODS FOR MODULATING APOLIPOPROTEIN C-III EXPRESSION IONIS PHARMACEUTICALS INC (US) 2026-02-05 US disclosed
US-20260022382-A1 Compositions and Methods for Modulating Complement Factor B Expression IONIS PHARMACEUTICALS, INC. (US) 2026-01-22 US disclosed
US-12516319-B2 Compositions and methods for modulating TTR expression IONIS PHARMACEUTICALS, INC. (US) 2026-01-06 US disclosed
US-12509684-B2 Compositions and methods for modulating apolipoprotein C-III expression IONIS PHARMACEUTICALS, INC. (US) 2025-12-30 US disclosed
US-20250346899-A1 CONJUGATED ANTISENSE COMPOUNDS AND THEIR USE IONIS PHARMACEUTICALS, INC. (US) 2025-11-13 US disclosed
US-12291709-B2 Compositions and methods for modulating apolipoprotein (a) expression IONIS PHARMACEUTICALS, INC. (US) 2025-05-06 US disclosed
US-12290567-B2 Asialoglycoprotein Receptor mediated delivery of therapeutically active conjugates ARCTURUS THERAPEUTICS, INC. (US) 2025-05-06 US disclosed
EP-1363876-A1 GLUCOCORTICOID RECEPTOR MODULATORS Abbott Laboratories (US) 2003-11-26 EP disclosed
US-6583180-B2 Antidiabetic agents ABBOTT LABORATORIES 2003-06-24 US disclosed
US-20020156311-A1 Glucocorticoid receptor modulators KARO BIO AB (SE) 2002-10-24 US disclosed
WO-2002064550-A1 GLUCOCORTICOID RECEPTOR MODULATORS ABBOTT LABORATORIES (US) 2002-08-22 WO disclosed
WO-1997049711-A1 DERIVATIVES OF CARBOXY GEM-BISPHOSPHONATES WITH ANTITUMOR ACTIVITY, A PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) 1997-12-31 WO disclosed
US-4154937-A ANGIOTENSIN CONVERTING ENZYME INHIBITORS E. R. SQUIBB & SONS, INC. (US) 1979-05-15 US disclosed
US-4128653-A Reduction of blood pressure with carboxyalkylacyl-pipecolic acid derivatives E. R. SQUIBB & SONS, INC. (US) 1978-12-05 US disclosed
US-4086338-A HYPOTENSIVE AGENTS, ANGIOTENSIN CONVERTING ENZYME INHIBITORS E. R. SQUIBB & SONS, INC. (US) 1978-04-25 US disclosed
US-4052511-A ANGIOTENSIN CONVERTING ENZYME INHIBITORS E. R. SQUIBB & SONS, INC. (US) 1977-10-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035695-A1 COMPOSITIONS AND METHODS FOR MODULATING APOLIPOPROTEIN C-III EXPRESSION APOL1, APOB, PCSK9 CPA3 611/4885CYP1A2 3894/4885CPA1 694/4885
US-12290567-B2 Asialoglycoprotein Receptor mediated delivery of therapeutically active conjugates ASGR1, FCGR2A, FCGR3B CPA3 618/4885CYP1A2 3138/4885CPA1 803/4885
US-20260022382-A1 Compositions and Methods for Modulating Complement Factor B Expression CFB, CFH, C5 CPA3 1275/4885CYP1A2 4296/4885CPA1 753/4885
US-20020156311-A1 Glucocorticoid receptor modulators NR3C1, NR5A1, NR3C2 CPA3 4073/4885CYP1A2 469/4885CPA1 2955/4885
US-12509684-B2 Compositions and methods for modulating apolipoprotein C-III expression APOB, APOL1, NSUN2 CPA3 1448/4885CYP1A2 4422/4885CPA1 1681/4885
US-12291709-B2 Compositions and methods for modulating apolipoprotein (a) expression APOB, APOL1, LDLR CPA3 1418/4885CYP1A2 2871/4885CPA1 542/4885
US-20250346899-A1 CONJUGATED ANTISENSE COMPOUNDS AND THEIR USE CSGALNACT1, GALNT1, GALNT6 CPA3 3397/4885CYP1A2 4804/4885CPA1 2288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.