Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 19/20 | 0.51 |
| ▸ | RARA | P10276 | 2/20 | 0.50 |
| ▸ | RARB | P10826 | 2/20 | 0.50 |
| ▸ | RARG | P13631 | 2/20 | 0.50 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2656899 | 0.84 | GCK (0.62) | GCKRARARARBRARGHCAR3 | |
| SCHEMBL2667937 | 0.80 | GCK (0.52) | GCKRARARARBRARGHCAR3 | |
| SCHEMBL9070821 | 0.79 | GCK (0.55) | GCKRARARARBRARGHCAR3 | |
| SCHEMBL9070896 | 0.77 | HCAR3 (0.52) | GCKRARARARBRARGHCAR3 | |
| SCHEMBL2657252 | 0.77 | GCK (0.53) | GCKRARARARBRARG | |
| SCHEMBL2667765 | 0.75 | GCK (0.65) | GCKRARARARBRARG | |
| SCHEMBL9070871 | 0.75 | GCK (0.66) | GCKRARARARBRARGHCAR3 | |
| SCHEMBL2667932 | 0.75 | GCK (0.51) | GCKRARARARBRARGHCAR3 | |
| SCHEMBL2667743 | 0.75 | GCK (0.63) | GCKRARARARBRARG | |
| SCHEMBL2667603 | 0.74 | GCK (0.53) | GCKRARARARBRARGHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |