Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NOS2 | P35228 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | FADS1 | O60427 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 3/20 | 0.41 |
| ▸ | GCK | P35557 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667962 | 0.81 | RECQL (0.49) | SMN1; SMN2TSHRCYP3A4ALDH1A1ALOX15 | |
| SCHEMBL8861494 | 0.80 | ALDH1A1 (0.54) | SMN1; SMN2TSHRCYP3A4ALDH1A1ALOX15 | |
| SCHEMBL2199382 | 0.78 | LMNA (0.45) | SMN1; SMN2ALDH1A1ALOX15HPGDALOX12 | |
| SCHEMBL620233 | 0.78 | RECQL (0.59) | SMN1; SMN2TSHRCYP3A4ALDH1A1ALOX15 | |
| SCHEMBL11828387 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2TSHRCYP3A4ALDH1A1ALOX15 | |
| SCHEMBL5742419 | 0.78 | CA1 (0.55) | SMN1; SMN2TSHRCYP3A4ALDH1A1ALOX15 | |
| SCHEMBL8278916 | 0.78 | RECQL (0.46) | SMN1; SMN2TSHRCYP3A4ALDH1A1ALOX15 | |
| Hydrochloric Acid SCHEMBL8012538 | 0.77 | RECQL (0.58) | SMN1; SMN2TSHRCYP3A4ALDH1A1ALOX15 | |
| SCHEMBL9540049 | 0.76 | RECQL (0.79) | SMN1; SMN2TSHRCYP3A4ALDH1A1ALOX15 | |
| SCHEMBL19350065 | 0.76 | TSHR (0.54) | SMN1; SMN2TSHRCYP3A4ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075847-A2 | GLUCOKINASE ACTIVATORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-07-05 | — | — | WO | disclosed |