Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.57 |
| ▸ | SCD | O00767 | 8/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | DHODH | Q02127 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | STAT1 | P42224 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | TOP1 | P11387 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9070897 | 0.89 | SCD (0.56) | NPC1SCDRAB9AMEN1KMT2A | |
| SCHEMBL2667947 | 0.83 | CASP3 (0.56) | NPC1SCDRAB9AMEN1KMT2A | |
| SCHEMBL4910923 | 0.82 | NPC1 (0.71) | NPC1SCDRAB9AMEN1KMT2A | |
| SCHEMBL4919472 | 0.81 | NPC1 (0.70) | NPC1SCDRAB9AMEN1KMT2A | |
| SCHEMBL9070899 | 0.79 | RAB9A (0.49) | NPC1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL2667713 | 0.79 | NPC1 (0.52) | NPC1SCDRAB9AMEN1KMT2A | |
| SCHEMBL9070898 | 0.78 | SMN1; SMN2 (0.56) | NPC1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL2667942 | 0.78 | RAB9A (0.62) | NPC1SCDRAB9AMEN1KMT2A | |
| SCHEMBL2667712 | 0.78 | NPC1 (0.53) | NPC1SCDRAB9AMEN1KMT2A | |
| SCHEMBL2667497 | 0.78 | SCD (0.52) | NPC1SCDRAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |