Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 13/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.62 |
| ▸ | MEN1 | O00255 | 6/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 12/20 | 0.57 |
| ▸ | PKM | P14618 | 6/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | KLF5 | Q13887 | 2/20 | 0.54 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.54 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.54 |
| ▸ | SCD | O00767 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667941 | 0.78 | NPC1 (0.57) | RAB9ASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL11705210 | 0.78 | RAB9A (0.55) | RAB9ASMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL11801720 | 0.75 | SPHK2 (0.68) | RAB9ASMN1; SMN2LMNAMAPTNPC1 | |
| SCHEMBL11715582 | 0.74 | SPHK2 (0.60) | RAB9ASMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL3926899 | 0.74 | NPC1 (1.00) | RAB9ASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL11207978 | 0.73 | RAB9A (1.00) | RAB9ASMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL9070896 | 0.73 | HCAR3 (0.52) | — | |
| SCHEMBL22193346 | 0.73 | RAB9A (1.00) | RAB9ASMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL11865449 | 0.72 | NPC1 (0.65) | RAB9ASMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL11703736 | 0.72 | NPC1 (0.91) | RAB9ASMN1; SMN2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |