Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.49 |
| ▸ | NPC1 | O15118 | 7/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9070898 | 0.81 | SMN1; SMN2 (0.56) | RAB9ANPC1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9070900 | 0.80 | RAB9A (0.55) | RAB9ANPC1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL2667943 | 0.79 | NPC1 (0.54) | RAB9ANPC1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL2667941 | 0.79 | NPC1 (0.57) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL9070896 | 0.76 | HCAR3 (0.52) | — | |
| SCHEMBL13870307 | 0.74 | ALDH1A1 (0.55) | RAB9ANPC1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL2664773 | 0.73 | ALDH1A1 (0.59) | RAB9ANPC1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL12742436 | 0.71 | SMN1; SMN2 (0.66) | RAB9ANPC1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL2667942 | 0.71 | RAB9A (0.62) | RAB9ANPC1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL10253052 | 0.69 | SMN1; SMN2 (0.65) | RAB9ALMNASMN1; SMN2MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |