Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCLRE1B | Q9H816 | 3/20 | 0.62 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.62 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.51 |
| ▸ | HNF4A | P41235 | 2/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.49 |
| ▸ | ACLY | P53396 | 2/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.48 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.48 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.48 |
| ▸ | DHFR | P00374 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7763818 | 0.85 | F13A1 (0.50) | DCLRE1BDCLRE1AACMSDHNF4AFFAR1 | |
| SCHEMBL4948042 | 0.81 | HDAC1 (0.52) | ACMSDHNF4AFFAR1PTGER1PTGER4 | |
| SCHEMBL7019419 | 0.81 | DCLRE1B (0.66) | DCLRE1BDCLRE1AACMSDHNF4AACLY | |
| SCHEMBL10786940 | 0.80 | HSD17B10 (0.46) | HDAC1SMN1; SMN2HDAC3MAPK1ADRA1A | |
| SCHEMBL30637100 | 0.80 | FOLH1 (0.61) | FFAR1HDAC1SMN1; SMN2HDAC3MAPK1 | |
| SCHEMBL9759595 | 0.80 | FOLH1 (0.61) | FFAR1HDAC1SMN1; SMN2HDAC3MAPK1 | |
| SCHEMBL10397478 | 0.78 | DCLRE1B (0.72) | DCLRE1BDCLRE1AACMSDHNF4AACLY | |
| SCHEMBL7734727 | 0.78 | FFAR1 (0.47) | FFAR1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL26679390 | 0.78 | TSHR (0.47) | PTGER1PTGER4PTGER3PTGER2HDAC1 | |
| SCHEMBL26679402 | 0.78 | F13A1 (0.43) | DCLRE1BFFAR1HDAC1SMN1; SMN2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522595-A2 | CATALYST-CONTROLLED SITE-SELECTIVE METHYLENE C-H LACTONIZATION OF DICARBOXYLIC ACIDS | The Scripps Research Institute (US) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023220559-A2 | CATALYST-CONTROLLED SITE-SELECTIVE METHYLENE C-H LACTONIZATION OF DICARBOXYLIC ACIDS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-11-16 | — | — | WO | disclosed |