Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26681332 | 0.89 | LMNA (0.47) | MEN1KMT2ALMNAMAPK1RAB9A | |
| SCHEMBL26683121 | 0.89 | MEN1 (0.43) | MEN1KMT2ALMNAMAPK1RAB9A | |
| SCHEMBL26683005 | 0.89 | MEN1 (0.44) | MEN1KMT2ALMNAMAPK1RAB9A | |
| SCHEMBL26681667 | 0.89 | KMT2A (0.42) | MEN1KMT2ALMNAITGB3ITGA2B | |
| SCHEMBL26682956 | 0.87 | ITGB3 (0.44) | CHRM4CHRM3ITGB3ITGA2BCHRM2 | |
| SCHEMBL26682082 | 0.83 | OPRD1 (0.44) | CHRM3ITGB3ITGA2BPPARDPPARA | |
| SCHEMBL30687743 | 0.81 | CHRM3 (0.46) | CHRM4CHRM3CHRM2DRD2DRD3 | |
| SCHEMBL26682995 | 0.81 | CHRM3 (0.46) | CHRM4CHRM3CHRM2DRD2DRD3 | |
| SCHEMBL26681477 | 0.81 | BCL2 (0.47) | KMT2ALMNACHRM4CHRM3ABL1 | |
| SCHEMBL26680364 | 0.81 | MAPT (0.61) | KMT2ALMNARAB9AABL1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4279476-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-11-22 | — | — | EP | disclosed |