Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 6/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | LSS | P48449 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26681870 | 0.91 | ITGB3 (0.43) | OPRD1OPRM1CHRM3ITGB3ITGA2B | |
| SCHEMBL26681257 | 0.89 | OPRD1 (0.45) | OPRD1OPRK1OPRM1CHRM3ITGB3 | |
| SCHEMBL26681657 | 0.89 | DRD2 (0.41) | OPRD1OPRK1OPRM1PPARDPPARA | |
| SCHEMBL26682956 | 0.88 | ITGB3 (0.44) | CHRM3PPARDPPARAITGB3ITGA2B | |
| SCHEMBL26682643 | 0.87 | OPRD1 (0.44) | OPRD1OPRK1OPRM1ITGB3ITGA2B | |
| SCHEMBL26682468 | 0.87 | OPRD1 (0.49) | OPRD1OPRK1OPRM1PPARDPPARA | |
| SCHEMBL30687743 | 0.85 | CHRM3 (0.46) | CHRM3 | |
| SCHEMBL26682995 | 0.85 | CHRM3 (0.46) | CHRM3 | |
| SCHEMBL30687628 | 0.84 | SLC6A9 (0.36) | OPRD1OPRK1OPRM1CHRM3PPARD | |
| SCHEMBL26682347 | 0.84 | SLC6A9 (0.36) | OPRD1OPRK1OPRM1CHRM3PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240132431-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-04-25 | — | — | US | disclosed |
| EP-4279476-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-11-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240132431-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | MGMT, MCL1, FANCF | OPRD1 3827/4885OPRK1 4067/4885OPRM1 2601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.