SCHEMBL26684789

SCHEMBL26684789

NN1C(=O)Cc2cc(Cl)c(Br)cc21

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ AHR P35869 2/20 0.32
▸ MEN1 O00255 3/20 0.31
▸ KMT2A Q03164 3/20 0.31
▸ GAA P10253 2/20 0.31
▸ MAPT P10636 1/20 0.30
▸ ALOX12 P18054 1/20 0.30
▸ CASP6 P55212 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16320915 0.72 PKM (0.41) MEN1KMT2AGAA
SCHEMBL12066807 0.71 AADAT (0.44) AHRMEN1KMT2AMAPTALOX12
SCHEMBL15241801 0.64 PDE5A (0.51) MEN1KMT2AGAACASP6
SCHEMBL19254922 0.64 GAA (0.43) MEN1KMT2AGAACASP6
SCHEMBL16310157 0.64 HSD17B10 (0.46) MEN1KMT2AGAACASP6
SCHEMBL9834030 0.62 NOTUM (0.37) MEN1KMT2AGAAMAPTALOX12
SCHEMBL1462133 0.62 HPGD (0.55) MEN1KMT2AMAPTCASP6
SCHEMBL8860186 0.61 ALDH1A1 (0.46) MEN1KMT2AGAA
SCHEMBL14779873 0.61 CYP11B2 (0.40) —
SCHEMBL27655357 0.60 BRD4 (0.47) GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119998278-A Compounds and uses thereof 福宏治疗公司 2025-05-13 — — CN disclosed
EP-4522278-A1 BENZOYPARAZINE PYRAZINES ANE THEIR USES Foghorn Therapeutics Inc. (US) 2025-03-19 — — EP disclosed
WO-2023220129-A1 BENZOYPARAZINE PYRAZINES ANE THEIR USES FOGHORN THERAPEUTICS INC. (US) 2023-11-16 — — WO disclosed
WO-2023220129-A1 BENZOYPARAZINE PYRAZINES ANE THEIR USES FOGHORN THERAPEUTICS INC. (US) 2023-11-16 — — WO disclosed
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