Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.32 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2661597 | 0.87 | HDAC8 (0.32) | HDAC8PLCG2 | |
| SCHEMBL13083371 | 0.80 | PLCG2 (0.38) | PLCG2ACKR3 | |
| SCHEMBL9072960 | 0.79 | PLCG2 (0.37) | PLCG2ACKR3 | |
| SCHEMBL2661595 | 0.78 | BDKRB1 (0.32) | HDAC8 | |
| SCHEMBL2976696 | 0.77 | PLCG2 (0.33) | PLCG2ACKR3 | |
| SCHEMBL2668839 | 0.74 | KDM4E (0.35) | PLCG2 | |
| SCHEMBL13083372 | 0.74 | ACHE (0.39) | PLCG2ACKR3 | |
| SCHEMBL2660077 | 0.74 | ALDH1A1 (0.36) | PLCG2 | |
| SCHEMBL2659017 | 0.74 | PLCG2 (0.34) | PLCG2ACKR3 | |
| SCHEMBL9073009 | 0.72 | PLCG2 (0.37) | PLCG2ACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008050821-A1 | INDOLE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-02 | — | — | WO | disclosed |