Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2668733 | 0.86 | NPC1 (0.49) | KDM4ESMN1; SMN2HSD17B10NPC1RAB9A | |
| SCHEMBL9071660 | 0.86 | OPRM1 (0.46) | OPRM1OPRD1BTK | |
| SCHEMBL2668510 | 0.81 | NPSR1 (0.44) | SMN1; SMN2NPC1RAB9AHTTHDAC6 | |
| SCHEMBL2668459 | 0.78 | KMT2A (0.43) | MEN1KMT2ABTK | |
| SCHEMBL9071880 | 0.78 | GHSR (0.47) | SMN1; SMN2HSD17B10NPC1RAB9APOLB | |
| SCHEMBL9071953 | 0.76 | NPC1 (0.47) | SMN1; SMN2NPC1RAB9APOLBMEN1 | |
| SCHEMBL2668712 | 0.75 | HTT (0.45) | SMN1; SMN2NPC1HTTMEN1KMT2A | |
| SCHEMBL2668624 | 0.75 | NPSR1 (0.52) | SMN1; SMN2HSD17B10RAB9AHTTPOLB | |
| SCHEMBL27736470 | 0.74 | KDM4E (0.56) | KDM4ESMN1; SMN2HSD17B10NPC1RAB9A | |
| SCHEMBL26347381 | 0.73 | NR1H4 (0.42) | RAB9AKMT2ATSHROPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007006814-A1 | UREA GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2007-01-18 | — | — | WO | disclosed |