Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | F2R | P25116 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9071880 | 0.87 | GHSR (0.47) | SMN1; SMN2ALDH1A1POLBHSD17B10RAB9A | |
| SCHEMBL9071953 | 0.85 | NPC1 (0.47) | SMN1; SMN2ALDH1A1LMNAPOLBTSHR | |
| SCHEMBL2668712 | 0.84 | HTT (0.45) | SMN1; SMN2ALDH1A1LMNAHTT | |
| SCHEMBL2668733 | 0.78 | NPC1 (0.49) | SMN1; SMN2ALDH1A1LMNATSHRHSD17B10 | |
| SCHEMBL2668459 | 0.77 | KMT2A (0.43) | — | |
| SCHEMBL2668510 | 0.77 | NPSR1 (0.44) | NPSR1SMN1; SMN2ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL9071660 | 0.77 | OPRM1 (0.46) | — | |
| SCHEMBL11140776 | 0.75 | RAB9A (0.71) | NPSR1SMN1; SMN2ALDH1A1KCNK3KCNK9 | |
| SCHEMBL2668637 | 0.75 | KDM4E (0.46) | SMN1; SMN2ALDH1A1LMNAPOLBTSHR | |
| SCHEMBL1242082 | 0.73 | NPSR1 (0.69) | NPSR1SMN1; SMN2ALDH1A1KCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007006814-A1 | UREA GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2007-01-18 | — | — | WO | disclosed |