Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | PTGIR | P43119 | 4/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2668510 | 0.83 | NPSR1 (0.44) | KMT2AALOX5PTGIRBTK | |
| SCHEMBL9071660 | 0.83 | OPRM1 (0.46) | ALOX5BTK | |
| SCHEMBL2668513 | 0.82 | ALOX5 (0.42) | ALOX5PTGIRPTGDR | |
| SCHEMBL2668733 | 0.81 | NPC1 (0.49) | KMT2AMEN1ALOX5BTKPKM | |
| SCHEMBL2668637 | 0.78 | KDM4E (0.46) | KMT2AMEN1BTK | |
| SCHEMBL9071880 | 0.78 | GHSR (0.47) | KMT2AMEN1 | |
| SCHEMBL2668624 | 0.77 | NPSR1 (0.52) | — | |
| SCHEMBL9071953 | 0.76 | NPC1 (0.47) | KMT2AMEN1 | |
| SCHEMBL2668512 | 0.76 | NPC1 (0.47) | ALOX5 | |
| SCHEMBL2668712 | 0.75 | HTT (0.45) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008084043-A1 | UREA GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2008-07-17 | — | — | WO | disclosed |