Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | CCR4 | P51679 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2668718 | 0.90 | BRD4 (0.44) | SLC40A1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2668826 | 0.87 | SLC40A1 (0.36) | SLC40A1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2974808 | 0.85 | POLB (0.36) | ALDH1A1POLBKMT2AMAPTHPGD | |
| SCHEMBL9073023 | 0.85 | SLC40A1 (0.37) | SLC40A1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2661075 | 0.84 | GLO1 (0.41) | SLC40A1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2660091 | 0.83 | NFKBIA (0.40) | ALDH1A1BRD4MEN1KMT2AMAPT | |
| SCHEMBL2668834 | 0.78 | HPGD (0.33) | ALDH1A1POLBKMT2AMAPTHPGD | |
| SCHEMBL2668736 | 0.78 | SLC40A1 (0.40) | SLC40A1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2972268 | 0.76 | ALDH1A1 (0.33) | ALDH1A1POLBKMT2AMAPTHPGD | |
| SCHEMBL2660220 | 0.76 | MMP2 (0.43) | SLC40A1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008050821-A1 | INDOLE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-02 | — | — | WO | disclosed |