Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS8 | O00214 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.35 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 3/20 | 0.33 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2660363 | 0.93 | GLO1 (0.36) | LGALS8ITGB3ITGA2BGLO1MAPT | |
| SCHEMBL2660667 | 0.90 | MAPT (0.35) | ITGB3ITGA2BMAPTSLC40A1ITGAV | |
| SCHEMBL2660669 | 0.87 | MAPT (0.34) | LGALS8ITGB3ITGA2BMAPTITGAV | |
| SCHEMBL2668802 | 0.86 | ITGB3 (0.33) | LGALS8ITGB3ITGA2BMAPTITGAV | |
| SCHEMBL2668612 | 0.86 | ITGB3 (0.33) | LGALS8ITGB3ITGA2BITGAV | |
| SCHEMBL2660450 | 0.83 | GLO1 (0.35) | LGALS8ITGB3ITGA2BGLO1MAPT | |
| SCHEMBL13360111 | 0.83 | GLO1 (0.34) | LGALS8ITGB3ITGA2BGLO1MAPT | |
| SCHEMBL2658758 | 0.81 | MAPT (0.33) | ITGB3ITGA2BMAPTSLC40A1ITGAV | |
| SCHEMBL13221826 | 0.80 | MAPT (0.34) | LGALS8ITGB3ITGA2BMAPTITGAV | |
| SCHEMBL13222226 | 0.80 | ITGB3 (0.33) | LGALS8ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008050821-A1 | INDOLE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-02 | — | — | WO | disclosed |