Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ITGAV | P06756 | 1/20 | 0.30 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13221707 | 0.94 | ITGB3 (0.33) | ITGB3ITGA2BPDE3BPDE3APOLB | |
| SCHEMBL2668802 | 0.92 | ITGB3 (0.33) | ITGB3ITGA2BITGAVLGALS8 | |
| SCHEMBL2659562 | 0.92 | DRD2 (0.33) | ITGB3ITGA2BPDE3BPDE3APOLB | |
| SCHEMBL13203945 | 0.91 | ITGB3 (0.32) | ITGB3ITGA2B | |
| SCHEMBL2659563 | 0.88 | ITGB3 (0.31) | ITGB3ITGA2BPDE3BPDE3APOLB | |
| SCHEMBL13222226 | 0.88 | ITGB3 (0.33) | ITGB3ITGA2BITGAVLGALS8 | |
| SCHEMBL2668804 | 0.86 | LGALS8 (0.35) | ITGB3ITGA2BITGAVLGALS8 | |
| SCHEMBL2660001 | 0.86 | ITGB3 (0.34) | ITGB3ITGA2BITGAVLGALS8 | |
| SCHEMBL2659492 | 0.85 | ITGB3 (0.33) | ITGB3ITGA2BPDE3BPDE3AITGAV | |
| SCHEMBL13203946 | 0.85 | ITGB3 (0.32) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2508524-A2 | Indole compound | Takeda Pharmaceutical Company Limited (JP) | 2012-10-10 | — | — | EP | disclosed |
| WO-2008050821-A1 | INDOLE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-02 | — | — | WO | disclosed |