Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 6/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ITGAV | P06756 | 1/20 | 0.31 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2668612 | 0.92 | ITGB3 (0.33) | ITGB3ITGA2BITGAVLGALS8 | |
| SCHEMBL2660508 | 0.92 | SYK (0.33) | ITGB3ITGA2BMAPTLMNATP53 | |
| SCHEMBL2659399 | 0.88 | SYK (0.32) | ITGB3ITGA2BMAPTLMNATP53 | |
| SCHEMBL13222226 | 0.87 | ITGB3 (0.33) | ITGB3ITGA2BITGAVLGALS8 | |
| SCHEMBL2668804 | 0.86 | LGALS8 (0.35) | ITGB3ITGA2BMAPTLMNATP53 | |
| SCHEMBL2660001 | 0.86 | ITGB3 (0.34) | ITGB3ITGA2BMAPTLMNATP53 | |
| SCHEMBL13221707 | 0.86 | ITGB3 (0.33) | ITGB3ITGA2BITGAVLGALS8 | |
| SCHEMBL2660810 | 0.85 | ITGB3 (0.34) | ITGB3ITGA2BMAPTLMNATP53 | |
| SCHEMBL2660815 | 0.85 | ITGB3 (0.35) | ITGB3ITGA2BMAPTLMNATP53 | |
| SCHEMBL2660035 | 0.85 | ITGB3 (0.33) | ITGB3ITGA2BMAPTLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2508524-A2 | Indole compound | Takeda Pharmaceutical Company Limited (JP) | 2012-10-10 | — | — | EP | disclosed |
| WO-2008050821-A1 | INDOLE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-02 | — | — | WO | disclosed |