Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 9/20 | 0.41 |
| ▸ | SLC40A1 | Q9NP59 | 6/20 | 0.41 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2966007 | 0.81 | GLO1 (0.41) | GLO1SLC40A1CGASMMP2CYP17A1 | |
| SCHEMBL13531747 | 0.72 | GLO1 (0.39) | GLO1SLC40A1CGASMMP2 | |
| SCHEMBL2961399 | 0.68 | — | — | |
| SCHEMBL3501853 | 0.66 | MMP2 (0.40) | GLO1SLC40A1MMP2 | |
| SCHEMBL2660723 | 0.66 | MMP2 (0.52) | GLO1SLC40A1MMP2CYP17A1 | |
| SCHEMBL2660982 | 0.66 | SLC40A1 (0.38) | GLO1SLC40A1MMP2 | |
| SCHEMBL2660318 | 0.65 | SLC40A1 (0.47) | GLO1SLC40A1MMP2CYP17A1 | |
| SCHEMBL2660310 | 0.64 | OXTR (0.33) | — | |
| SCHEMBL2660222 | 0.63 | SLC40A1 (0.41) | GLO1SLC40A1MMP2 | |
| SCHEMBL2660729 | 0.63 | SLC40A1 (0.47) | GLO1SLC40A1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2508524-A2 | Indole compound | Takeda Pharmaceutical Company Limited (JP) | 2012-10-10 | — | — | EP | disclosed |
| WO-2008050821-A1 | INDOLE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-02 | — | — | WO | disclosed |