Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1320202 | 0.82 | UGT2B7 (0.59) | CYP1A2MMP9SLC6A4KCNH2UGT2B7 | |
| SCHEMBL13804034 | 0.82 | UGT2B7 (0.59) | CYP1A2MMP9SLC6A4KCNH2UGT2B7 | |
| SCHEMBL178531 | 0.82 | UGT2B7 (0.59) | CYP1A2MMP9SLC6A4KCNH2UGT2B7 | |
| SCHEMBL7915628 | 0.79 | CYP2A6 (0.62) | CYP1A2CYP2A6TDP1ALDH1A1UGT2B7 | |
| SCHEMBL30253980 | 0.79 | CYP2A6 (0.62) | CYP1A2CYP2A6TDP1ALDH1A1UGT2B7 | |
| SCHEMBL8285887 | 0.78 | ALDH1A1 (0.52) | TDP1ALDH1A1HTR2ASLC6A4KCNH2 | |
| SCHEMBL8284259 | 0.78 | ALDH1A1 (0.52) | TDP1ALDH1A1HTR2ASLC6A4KCNH2 | |
| SCHEMBL178538 | 0.78 | ALDH1A1 (0.52) | TDP1ALDH1A1HTR2ASLC6A4KCNH2 | |
| SCHEMBL24258312 | 0.77 | ALOX5 (0.60) | CYP1A2CYP2A6TDP1ALOX5CYP2D6 | |
| SCHEMBL2669155 | 0.75 | ACHE (0.46) | CYP1A2ALDH1A1SLC6A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8883824-B2 | 3-(4-aminophenyl)-2-furancarboxylic acid derivative and pharmaceutically acceptable salt thereof | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2014-11-11 | — | — | US | disclosed |
| EP-2431362-A1 | 3-(4-AMINOPHENYL)-2-FURANCARBOXYLIC ACID DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010131669-A1 | 3-(4-AMINOPHENYL)-2-FURANCARBOXYLIC ACID DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | 大日本住友製薬株式会社 (JP) | 2010-11-18 | — | — | WO | disclosed |