Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.41 |
| ▸ | GCK | P35557 | 5/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | PPM1D | O15297 | 1/20 | 0.36 |
| ▸ | F2RL1 | P55085 | 2/20 | 0.36 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.35 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9072816 | 0.90 | CTSL (0.45) | CTSLGCKUSP30CTSSPPM1D | |
| SCHEMBL2669291 | 0.86 | SMN1; SMN2 (0.45) | CTSLGCKUSP30CTSSPPM1D | |
| SCHEMBL2669250 | 0.86 | PSEN1 (0.44) | CTSLGCKUSP30CTSSPPM1D | |
| SCHEMBL2669154 | 0.85 | CTSL (0.43) | CTSLGCKUSP30CTSSPPM1D | |
| SCHEMBL2669300 | 0.84 | CTSL (0.43) | CTSLGCKUSP30CTSSPPM1D | |
| SCHEMBL2669256 | 0.84 | CTSS (0.46) | CTSLGCKCTSSF2RL1CTSB | |
| SCHEMBL2669285 | 0.81 | CTSL (0.36) | CTSLGCKUSP30CTSSF2RL1 | |
| SCHEMBL2669262 | 0.80 | PSEN1 (0.51) | CTSLCTSSF2RL1CTSK | |
| SCHEMBL2669260 | 0.80 | PSEN1 (0.43) | CTSLGCKCTSSCTSK | |
| SCHEMBL2669063 | 0.80 | CTSL (0.47) | CTSLGCKUSP30CTSSF2RL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007104034-A2 | GLUCOKINASE ACTIVATORS | TAKEDA SAN DIEGO, INC. (US) | 2007-09-13 | — | — | WO | disclosed |