Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 3/20 | 0.55 |
| ▸ | CPS1 | P31327 | 14/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9071945 | 0.95 | GCK (0.55) | GCKCPS1 | |
| SCHEMBL2669283 | 0.91 | GCK (0.66) | GCKCPS1GPR119 | |
| SCHEMBL2669367 | 0.91 | GCK (0.55) | GCKCPS1 | |
| SCHEMBL9923383 | 0.89 | GCK (0.53) | GCKCPS1 | |
| SCHEMBL9071966 | 0.86 | GCK (0.53) | GCK | |
| SCHEMBL2669236 | 0.86 | GCK (0.49) | GCK | |
| SCHEMBL9923388 | 0.84 | GCK (0.49) | GCK | |
| SCHEMBL2645627 | 0.84 | GCK (0.58) | GCKCPS1GPR119 | |
| SCHEMBL2669385 | 0.83 | GCK (0.67) | GCKCPS1GPR119 | |
| SCHEMBL2669341 | 0.82 | GCK (0.59) | GCKCPS1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007122482-A1 | FUSED PHENYL AMIDO HETEROCYCLIC COMPOUNDS FOR THE PREVENTION AND TREATMENT OF GLUCOKINASE-MEDIATED DISEASES | PFIZER PRODUCTS INC. (US) | 2007-11-01 | — | — | WO | disclosed |