Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2669358 | 0.91 | GCK (0.46) | GCK | |
| SCHEMBL15780551 | 0.90 | GCK (0.42) | GCK | |
| SCHEMBL9071966 | 0.89 | GCK (0.53) | GCKEZH2 | |
| SCHEMBL2669366 | 0.88 | GCK (0.50) | GCKEZH2 | |
| SCHEMBL2669283 | 0.87 | GCK (0.66) | GCKEZH2 | |
| SCHEMBL9923388 | 0.87 | GCK (0.49) | GCKEZH2 | |
| SCHEMBL2669286 | 0.86 | GCK (0.55) | GCK | |
| SCHEMBL9923373 | 0.86 | GCK (0.38) | GCKEZH2 | |
| SCHEMBL2669367 | 0.84 | GCK (0.55) | GCKEZH2 | |
| SCHEMBL9071945 | 0.84 | GCK (0.55) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2463283-A1 | Fused phenyl Amido heterocyclic compounds for the prevention and treatment of glucokinase-mediated diseases | Pfizer Products Inc. (US) | 2012-06-13 | — | — | EP | disclosed |
| WO-2007122482-A1 | FUSED PHENYL AMIDO HETEROCYCLIC COMPOUNDS FOR THE PREVENTION AND TREATMENT OF GLUCOKINASE-MEDIATED DISEASES | PFIZER PRODUCTS INC. (US) | 2007-11-01 | — | — | WO | disclosed |