Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6234780 | 0.83 | HTR1A (0.47) | HTR1AADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL6244574 | 0.83 | IDO1 (0.44) | MAOBHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL6237597 | 0.79 | CHRM2 (0.47) | HTR1AADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL6239312 | 0.79 | SMN1; SMN2 (0.52) | HTR1AADRA1DADRA1AADRA1BSPHK2 | |
| SCHEMBL2669347 | 0.78 | MAOB (0.43) | MAOBSLC1A5KDM4EALDH1A1CHRM3 | |
| SCHEMBL6928724 | 0.77 | MAOB (0.47) | MAOBSLC1A5KDM4EALDH1A1HPGD | |
| SCHEMBL6237705 | 0.77 | RAB9A (0.45) | MAOBALDH1A1SPHK2SPHK1MAPT | |
| SCHEMBL21518156 | 0.75 | HTR1B (0.46) | MAOBHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL29641278 | 0.74 | HTR1A (0.36) | MAOBHTR1AADRA1DADRA1AADRA1B | |
| Trifluoroacetic Acid SCHEMBL7760506 | 0.72 | SMN1; SMN2 (0.46) | SPHK2SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005011697-A2 | SULFONAMIDE DERIVATIVES WITH ACTIVITY ON PROTEIN KINASE A AND B | ASTEX THERAPEUTICS LIMITED (GB) | 2005-02-10 | — | — | WO | disclosed |