Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2669236 | 0.91 | GCK (0.49) | GCK | |
| SCHEMBL9923388 | 0.88 | GCK (0.49) | GCK | |
| SCHEMBL9071966 | 0.85 | GCK (0.53) | GCK | |
| SCHEMBL2643802 | 0.84 | GCK (0.48) | GCK | |
| SCHEMBL15780551 | 0.83 | GCK (0.42) | GCK | |
| SCHEMBL2669283 | 0.83 | GCK (0.66) | GCK | |
| SCHEMBL2669286 | 0.82 | GCK (0.55) | GCK | |
| SCHEMBL2669365 | 0.81 | GCK (0.46) | GCK | |
| SCHEMBL2669367 | 0.80 | GCK (0.55) | GCK | |
| SCHEMBL9071945 | 0.80 | GCK (0.55) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2463283-A1 | Fused phenyl Amido heterocyclic compounds for the prevention and treatment of glucokinase-mediated diseases | Pfizer Products Inc. (US) | 2012-06-13 | — | — | EP | disclosed |
| WO-2007122482-A1 | FUSED PHENYL AMIDO HETEROCYCLIC COMPOUNDS FOR THE PREVENTION AND TREATMENT OF GLUCOKINASE-MEDIATED DISEASES | PFIZER PRODUCTS INC. (US) | 2007-11-01 | — | — | WO | disclosed |