Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVR1 | Q04771 | 7/20 | 0.34 |
| ▸ | ACVRL1 | P37023 | 6/20 | 0.34 |
| ▸ | BMPR1A | P36894 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.30 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2669509 | 0.90 | ACVR1 (0.40) | ACVR1ACVRL1BMPR1APOLBPARP1 | |
| SCHEMBL2661471 | 0.88 | HSD11B1 (0.36) | ACVR1ACVRL1BMPR1APOLBPARP1 | |
| SCHEMBL2669394 | 0.87 | GRM5 (0.36) | ACVR1ACVRL1BMPR1APOLBPARP1 | |
| SCHEMBL4924879 | 0.85 | TSHR (0.35) | ACVR1ACVRL1BMPR1APOLBPARP1 | |
| SCHEMBL2656099 | 0.84 | PARP1 (0.35) | ACVR1ACVRL1BMPR1APOLBPARP1 | |
| SCHEMBL2669396 | 0.81 | PARP1 (0.35) | ACVR1ACVRL1BMPR1APOLBPARP1 | |
| SCHEMBL2660877 | 0.81 | MAPK1 (0.43) | POLBPARP1HTTESR2MAPK1 | |
| SCHEMBL2669594 | 0.81 | BMPR1A (0.40) | ACVR1ACVRL1BMPR1APOLBPARP1 | |
| SCHEMBL2657795 | 0.81 | HSP90AA1 (0.39) | ACVR1ACVRL1BMPR1APOLBPARP1 | |
| SCHEMBL2669424 | 0.80 | MAPK1 (0.36) | ACVR1ACVRL1BMPR1APOLBPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008155572-A2 | FUSED QUINOLINE DERIVATIVES USEFUL AS GABA MODULATORS | ASTRAZENECA AB (SE) | 2008-12-24 | — | — | WO | disclosed |