Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.35 |
| ▸ | NAMPT | P43490 | 5/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | GCG | P01275 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.30 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2669941 | 0.82 | TP53 (0.36) | NAMPT | |
| SCHEMBL2669956 | 0.81 | MAOB (0.35) | NAMPTALDH1A1ADRB2 | |
| SCHEMBL2669894 | 0.79 | GCGR (0.43) | GCG | |
| SCHEMBL2669992 | 0.77 | NAMPT (0.32) | NAMPTALDH1A1 | |
| SCHEMBL2669811 | 0.75 | TP53 (0.34) | — | |
| SCHEMBL2669810 | 0.75 | NAMPT (0.34) | NAMPT | |
| SCHEMBL9070776 | 0.75 | KMT2A (0.37) | ALDH1A1TBXAS1 | |
| SCHEMBL2669900 | 0.74 | NAMPT (0.35) | NAMPTTBXAS1 | |
| SCHEMBL9070778 | 0.74 | PTGS2 (0.42) | NAMPTHDAC6GCG | |
| SCHEMBL13069674 | 0.74 | FFAR4 (0.34) | HDAC6GCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110520-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-09-11 | — | — | WO | disclosed |