Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2669941 | 0.90 | TP53 (0.36) | NAMPTBRD4TP53MAPTPIK3CB | |
| SCHEMBL2669899 | 0.85 | NAMPT (0.36) | NAMPTPIK3CB | |
| SCHEMBL2669847 | 0.81 | NAMPT (0.36) | NAMPTBRD4PIK3CB | |
| SCHEMBL2669784 | 0.81 | NAMPT (0.33) | NAMPTMAPTKMT2ANPC1RAB9A | |
| SCHEMBL9070776 | 0.81 | KMT2A (0.37) | KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2669769 | 0.80 | NAMPT (0.36) | NAMPTBRD4TP53PIK3CBKMT2A | |
| SCHEMBL2669811 | 0.80 | TP53 (0.34) | TP53MAPTKMT2ANPC1RAB9A | |
| SCHEMBL2669956 | 0.78 | MAOB (0.35) | NAMPTTP53MAPTKMT2AMEN1 | |
| SCHEMBL2669992 | 0.75 | NAMPT (0.32) | NAMPTMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2669820 | 0.75 | FAAH (0.35) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110520-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-09-11 | — | — | WO | disclosed |