Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.31 |
| ▸ | MAP1LC3A | Q9H492 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2669941 | 0.79 | TP53 (0.36) | NAMPTMEN1LMNAMAPTKMT2A | |
| SCHEMBL2669820 | 0.77 | FAAH (0.35) | NAMPTALDH1A1 | |
| SCHEMBL2669956 | 0.76 | MAOB (0.35) | NAMPTMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL2669810 | 0.75 | NAMPT (0.34) | NAMPTMEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL9070776 | 0.75 | KMT2A (0.37) | KDM4ELMNAKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2669900 | 0.71 | NAMPT (0.35) | NAMPT | |
| SCHEMBL2669769 | 0.69 | NAMPT (0.36) | NAMPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2669895 | 0.69 | ESR1 (0.42) | MEN1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL2669811 | 0.69 | TP53 (0.34) | MEN1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL9070790 | 0.69 | NAMPT (0.34) | NAMPTKDM4EMEN1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110520-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-09-11 | — | — | WO | disclosed |