Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | GLA | P06280 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14856800 | 0.89 | HAO1 (0.38) | LMNACYP3A4KDM4EKMT2AMAPT | |
| SCHEMBL26698294 | 0.81 | ACHE (0.46) | KDM4EGLAPOLBGAAACHE | |
| SCHEMBL4810016 | 0.76 | TUBB4A (0.47) | LMNAKDM4EGAACA12CA9 | |
| SCHEMBL27836474 | 0.76 | ALDH1A1 (0.58) | LMNAPOLBGAATDP1ACHE | |
| SCHEMBL31598867 | 0.76 | TUBB4A (0.37) | LMNAKDM4EKMT2AMAPT | |
| SCHEMBL16776508 | 0.74 | TUBB4A (0.36) | KDM4EKMT2A | |
| SCHEMBL27593738 | 0.74 | TUBB4A (0.49) | LMNACYP3A4KDM4EGLAPOLB | |
| SCHEMBL20072247 | 0.74 | CYP2A6 (0.47) | LMNACYP3A4KDM4EGLAPOLB | |
| SCHEMBL29518325 | 0.74 | TUBB4A (0.49) | LMNACYP3A4KDM4EGLAPOLB | |
| SCHEMBL31655715 | 0.74 | KDM4E (0.47) | LMNACYP3A4KDM4EGLAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023226965-A1 | ROCK INHIBITORS AND USES THEREOF | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2023-11-30 | — | — | WO | disclosed |