Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 9/20 | 0.55 |
| ▸ | MGAM | O43451 | 7/20 | 0.55 |
| ▸ | AMY1A | P0DUB6 | 7/20 | 0.55 |
| ▸ | SI | P14410 | 7/20 | 0.55 |
| ▸ | MGAM2 | Q2M2H8 | 7/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | SLC9A1 | P19634 | 3/20 | 0.53 |
| ▸ | APAF1 | O14727 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13604166 | 0.86 | SLC9A1 (0.56) | EGLN3GAAMGAMAMY1ASI | |
| SCHEMBL13604165 | 0.83 | MGAM (0.62) | EGLN3GAAMGAMAMY1ASI | |
| SCHEMBL15479156 | 0.82 | SLC9A1 (0.55) | EGLN3GAAMGAMAMY1ASI | |
| SCHEMBL14336224 | 0.81 | SLC9A1 (0.50) | EGLN3GAAMGAMAMY1ASI | |
| SCHEMBL2070662 | 0.80 | GAA (0.67) | EGLN3GAAMGAMAMY1ASI | |
| SCHEMBL5017651 | 0.80 | SLC9A1 (0.59) | EGLN3GAAMGAMAMY1ASI | |
| SCHEMBL12001037 | 0.80 | SLC9A1 (0.59) | EGLN3GAAMGAMAMY1ASI | |
| SCHEMBL6846939 | 0.76 | EGLN3 (0.68) | EGLN3GAAMGAMAMY1ASI | |
| SCHEMBL446010 | 0.76 | EGLN3 (0.55) | EGLN3GAAMGAMAMY1ASI | |
| SCHEMBL2521622 | 0.76 | SLC9A1 (0.51) | EGLN3GAAMGAMAMY1ASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023226965-A1 | ROCK INHIBITORS AND USES THEREOF | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2023-11-30 | — | — | WO | disclosed |