Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | GCG | P01275 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | CCKBR | P32239 | 2/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2669769 | 0.90 | NAMPT (0.36) | NAMPTGCGHDAC6HDAC3HDAC1 | |
| SCHEMBL2669899 | 0.87 | NAMPT (0.36) | NAMPTGCGHDAC6HDAC3HDAC1 | |
| SCHEMBL2669810 | 0.81 | NAMPT (0.34) | NAMPTBRD4PIK3CB | |
| SCHEMBL13069831 | 0.81 | NPC1 (0.33) | — | |
| SCHEMBL2669941 | 0.81 | TP53 (0.36) | NAMPTHDAC3HDAC1BRD4PIK3CB | |
| SCHEMBL2669953 | 0.80 | BTK (0.41) | GCGHDAC6HDAC1PIK3CB | |
| SCHEMBL9070790 | 0.80 | NAMPT (0.34) | NAMPTGCG | |
| SCHEMBL2669835 | 0.80 | SRC (0.33) | NAMPTGCGHDAC6HDAC3HDAC1 | |
| SCHEMBL13069228 | 0.80 | TP53 (0.34) | GCG | |
| SCHEMBL2669991 | 0.80 | NAMPT (0.40) | NAMPTGCGHDAC6HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110520-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-09-11 | — | — | WO | disclosed |