SCHEMBL26699754

SCHEMBL26699754

CC/C=C/CC(OCC(C)Cc1ccc(Cl)cc1)C(=O)NN

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSC P53634 1/20 0.38
ACACB O00763 1/20 0.36
FPR2 P25090 1/20 0.35
PPARG P37231 6/20 0.35
PPARA Q07869 6/20 0.35
HTT P42858 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A3 Q01959 1/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
MMP2 P08253 1/20 0.34
CA9 Q16790 1/20 0.34
LMNA P02545 1/20 0.34
POLB P06746 1/20 0.34
KMT2A Q03164 1/20 0.34
CNR1 P21554 3/20 0.34
CNR2 P34972 2/20 0.34
HDAC3 O15379 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC1 Q13547 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26700528 0.76 GAA (0.40) CTSCACACBFPR2PPARGPPARA
SCHEMBL26699433 0.74 TSHR (0.46) CTSCACACBFPR2PPARGPPARA
SCHEMBL26699700 0.73 NOS2 (0.45) CTSCACACBFPR2PPARGPPARA
SCHEMBL28564655 0.68 PPARG (0.48) PPARGPPARALMNA
SCHEMBL28564654 0.68 PPARG (0.48) PPARGPPARALMNA
SCHEMBL26698133 0.66 PPARG (0.44) ACACBFPR2PPARGPPARASLC6A2
SCHEMBL26700131 0.65 SLC6A2 (0.46) CTSCACACBFPR2PPARGPPARA
SCHEMBL6763614 0.63 PPARA (0.49) PPARGPPARA
SCHEMBL20397624 0.63 KMT2A (0.51) CTSCACACBPPARGPPARACA2
SCHEMBL18262597 0.63 KMT2A (0.51) CTSCACACBPPARGPPARACA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4269400-A1 YKL-40 INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS Molecure SA (PL) 2023-11-01 EP disclosed