SCHEMBL2672258

SCHEMBL2672258

O=C(F)C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 4/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
EPHX1 P07099 1/20 0.42
EPHX2 P34913 1/20 0.42
HTT P42858 2/20 0.42
ALDH1A1 P00352 2/20 0.42
CRHBP P24387 1/20 0.42
CRHR2 Q13324 1/20 0.42
MCOLN3 Q8TDD5 1/20 0.42
GLA P06280 1/20 0.42
KDM4E B2RXH2 1/20 0.41
GAA P10253 2/20 0.39
MAPT P10636 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
XBP1 P17861 1/20 0.39
P2RX7 Q99572 1/20 0.39
LMNA P02545 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL251840 0.77 HSD11B1 (0.50) HSD11B1L3MBTL1EPHX1EPHX2HTT
SCHEMBL12714 0.74 HSD11B1 (0.48) HSD11B1L3MBTL1EPHX1EPHX2HTT
SCHEMBL133056 0.74 HSD11B1 (0.48) HSD11B1L3MBTL1EPHX1EPHX2HTT
SCHEMBL19557166 0.74 HSD11B1 (0.48) HSD11B1L3MBTL1EPHX1EPHX2HTT
SCHEMBL19557168 0.74 HSD11B1 (0.48) HSD11B1L3MBTL1EPHX1EPHX2HTT
Ammonia Solution, Strong SCHEMBL11787415 0.74 HSD11B1 (0.48) HSD11B1L3MBTL1EPHX1EPHX2HTT
SCHEMBL546352 0.74 HTT (0.48) HSD11B1L3MBTL1EPHX1EPHX2HTT
SCHEMBL3843956 0.74 HSD11B1 (0.44) HSD11B1L3MBTL1EPHX1EPHX2HTT
SCHEMBL13085219 0.72 HSD11B1 (0.46) HSD11B1L3MBTL1EPHX1EPHX2HTT
SCHEMBL5489940 0.72 HSD11B1 (0.46) HSD11B1L3MBTL1EPHX1EPHX2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117903112-A Sulfur-containing deoxidized fluoridation reagent and preparation method and application thereof 铜陵学院 2024-04-19 CN disclosed
CN-112174761-B Fluorination method 三明市海斯福化工有限责任公司 2023-03-24 CN disclosed
US-20210155561-A1 METHOD AND REAGENT FOR DEOXYFLUORINATION SOUTH DAKOTA BOARD OF REGENTS (US) 2021-05-27 US disclosed
US-8173297-B2 Improved high-temperature storage and cycle characteristics; succinyl chloride or succinyl fluoride as solvent; computers SONY CORPORATION (JP) 2012-05-08 US disclosed
CN-101132083-B Electrolytic solution and battery SONY CORP 2010-12-15 CN disclosed
US-20080076031-A1 ELECTROLYTIC SOLUTION AND BATTERY SONY CORPORATION (JP) 2008-03-27 US disclosed
CN-101132083-A Electrolytic solution and battery SONY CORP (JP) 2008-02-27 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210155561-A1 METHOD AND REAGENT FOR DEOXYFLUORINATION PFAS, FIBP, NPFFR2 HSD11B1 2724/4885L3MBTL1 4692/4885EPHX1 2891/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.