Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6337559 | 1.00 | CTSL (0.80) | CTSLCTSB | |
| SCHEMBL2675409 | 0.95 | CTSL (0.86) | CTSLCTSB | |
| SCHEMBL6337649 | 0.91 | CTSL (0.84) | CTSLCTSB | |
| SCHEMBL18529840 | 0.88 | CTSL (1.00) | CTSLCTSB | |
| SCHEMBL6338501 | 0.88 | CTSL (0.75) | CTSLCTSB | |
| SCHEMBL6337731 | 0.88 | CTSL (1.00) | CTSLCTSB | |
| SCHEMBL31174804 | 0.88 | CTSL (1.00) | CTSLCTSB | |
| SCHEMBL18540692 | 0.88 | CTSL (1.00) | CTSLCTSB | |
| SCHEMBL29543636 | 0.88 | CTSL (1.00) | CTSLCTSB | |
| SCHEMBL18540696 | 0.87 | CTSL (0.92) | CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173696-B2 | Inhibitors of cysteine proteases and methods of use thereof | BAYLOR UNIVERSITY (US) | 2012-05-08 | — | — | US | disclosed |
| US-20090076076-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | BAYLOR UNIVERSITY (US) | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090076076-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | CTSB, CTSS, CTSZ | CTSL 6/4885CTSB 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.