Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.49 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.42 |
| ▸ | PRKCA | P17252 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26754286 | 0.83 | PRKCA (0.41) | NLRP3PRKCA | |
| SCHEMBL26754297 | 0.81 | PRKCA (0.42) | PRKCA | |
| SCHEMBL15274796 | 0.81 | ALDH1A1 (0.41) | NLRP3LPAR1PRKCA | |
| SCHEMBL14020001 | 0.79 | NLRP3 (0.46) | NLRP3LPAR1LPAR3ENPP2 | |
| SCHEMBL25848491 | 0.79 | LPAR1 (0.39) | LPAR1PRKCA | |
| SCHEMBL57588 | 0.78 | ALDH1A1 (0.52) | NLRP3 | |
| SCHEMBL20617446 | 0.78 | NLRP3 (0.44) | NLRP3PRKCA | |
| SCHEMBL78535 | 0.78 | ALDH1A1 (0.52) | NLRP3 | |
| SCHEMBL78536 | 0.78 | ALDH1A1 (0.52) | NLRP3 | |
| SCHEMBL5725620 | 0.78 | LMNA (0.47) | NLRP3LPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11814360-B2 | Isocyanates, derivatives, and processes for producing the same | NOVOMER, INC. (US) | 2023-11-14 | — | — | US | disclosed |
| US-11814498-B2 | Polylactone foams and methods of making the same | NOVOMER, INC. (US) | 2023-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11814360-B2 | Isocyanates, derivatives, and processes for producing the same | IDH1, IDH2, IDH3A | NLRP3 4094/4885LPAR1 4218/4885LPAR3 4021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.