⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26192652 | 1.00 | — | — | |
| SCHEMBL16629083 | 0.81 | — | — | |
| SCHEMBL20980231 | 0.80 | ADRB2 (0.32) | — | |
| SCHEMBL21465897 | 0.76 | EPHX1 (0.32) | — | |
| SCHEMBL21465912 | 0.75 | HDAC3 (0.41) | — | |
| SCHEMBL21465896 | 0.74 | — | — | |
| SCHEMBL23747679 | 0.70 | CTSL (0.31) | — | |
| SCHEMBL17973547 | 0.70 | ACE (0.40) | — | |
| SCHEMBL2625030 | 0.70 | ALDH1A1 (0.35) | — | |
| SCHEMBL13213430 | 0.70 | TGFBR1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357342-A1 | MODIFIED IL-18 POLYPEPTIDES | BRIGHT PEAK THERAPEUTICS AG (CH) | 2023-11-09 | — | — | US | disclosed |