SCHEMBL26761406

SCHEMBL26761406

c1ccc(-c2cccc(-c3cccc4c3oc3cccc(-c5c6ccccc6c(-c6ccccc6)c6cc(-c7ccccc7)ccc56)c34)c2)cc1

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 2/20 0.45
▸ PRKDC P78527 10/20 0.40
▸ PLA2G2A P14555 3/20 0.38
▸ PLA2G4A P47712 3/20 0.38
▸ PLA2G10 O15496 1/20 0.38
▸ GGPS1 O95749 1/20 0.37
▸ PTGES2 Q9H7Z7 1/20 0.34
▸ PIM1 P11309 1/20 0.33
▸ CSNK2A2 P19784 1/20 0.33
▸ CSNK2B P67870 1/20 0.33
▸ PIM3 Q86V86 1/20 0.33
▸ PIM2 Q9P1W9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25624590 0.96 ALOX5 (0.43) ALOX5PRKDCPLA2G2APLA2G4APLA2G10
SCHEMBL25624613 0.96 ALOX5 (0.43) ALOX5PRKDCPLA2G2APLA2G4APLA2G10
SCHEMBL25624550 0.96 ALOX5 (0.43) ALOX5PRKDCPLA2G2APLA2G4APLA2G10
SCHEMBL19770483 0.95 ALOX5 (0.46) ALOX5PRKDCPLA2G2APLA2G4APLA2G10
SCHEMBL25624509 0.94 ALOX5 (0.46) ALOX5PRKDCPLA2G2APLA2G4APLA2G10
SCHEMBL25624543 0.91 ALOX5 (0.48) ALOX5PRKDCPLA2G2APLA2G4APLA2G10
SCHEMBL25624581 0.90 CA12 (0.41) ALOX5PRKDCPLA2G2APLA2G4APLA2G10
SCHEMBL22707211 0.90 ALOX5 (0.46) ALOX5PRKDCPLA2G2APLA2G4APLA2G10
SCHEMBL10442466 0.90 ALOX5 (0.57) ALOX5PRKDCPLA2G2APLA2G4APLA2G10
SCHEMBL10442588 0.90 ALOX5 (0.57) ALOX5PRKDCPLA2G2APLA2G4APLA2G10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230371376-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME SFC CO., LTD. (KR) 2023-11-16 — — US disclosed
US-20230371376-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME SFC CO., LTD. (KR) 2023-11-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230371376-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME PPOX, MAP1LC3A, VDAC2 ALOX5 870/4885PRKDC 2818/4885PLA2G2A 1893/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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