SCHEMBL26770100

SCHEMBL26770100

CC(C)CN(CC(=O)NO)S(=O)(=O)c1ccc(O)cc1

nearest known ligand 0.76

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MMP3 P08254 10/20 0.76
MMP13 P45452 9/20 0.74
MMP1 P03956 8/20 0.74
MMP8 P22894 8/20 0.74
MMP2 P08253 4/20 0.74
MMP14 P50281 4/20 0.74
MMP9 P14780 3/20 0.74
ADAM17 P78536 1/20 0.74
ADAMTS4 O75173 1/20 0.67
ADAMTS5 Q9UNA0 1/20 0.67
MMP7 P09237 5/20 0.57
MMP12 P39900 5/20 0.57
TAS2R14 Q9NYV8 1/20 0.55
MEP1B Q16820 1/20 0.51
BMP1 P13497 1/20 0.50
MMP16 P51512 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7347286 0.89 MMP3 (0.76) MMP3MMP13MMP1MMP8MMP2
SCHEMBL7340897 0.89 MMP3 (0.76) MMP3MMP13MMP1MMP8MMP2
SCHEMBL7349859 0.87 MMP3 (0.74) MMP3MMP13MMP1MMP8MMP2
SCHEMBL7343386 0.87 MMP3 (0.74) MMP3MMP13MMP1MMP8MMP2
SCHEMBL7343903 0.87 MMP3 (0.74) MMP3MMP13MMP1MMP8MMP2
SCHEMBL7351771 0.87 MMP3 (0.85) MMP3MMP13MMP1MMP8MMP2
SCHEMBL7343818 0.86 MMP3 (1.00) MMP3MMP13MMP1MMP8MMP2
SCHEMBL598146 0.85 MMP3 (0.79) MMP3MMP13MMP1MMP8MMP2
SCHEMBL26770282 0.85 MMP3 (0.70) MMP3MMP13MMP1MMP8MMP2
SCHEMBL7342296 0.84 MMP3 (0.69) MMP3MMP13MMP1MMP8MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357139-A1 SMALL MOLECULE INHIBITORS OF BACTERIAL TOXINS Artizan Biosciences, Inc. 2023-11-09 US disclosed
US-20230357139-A1 SMALL MOLECULE INHIBITORS OF BACTERIAL TOXINS Artizan Biosciences, Inc. 2023-11-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357139-A1 SMALL MOLECULE INHIBITORS OF BACTERIAL TOXINS FABP2, APC, SI MMP3 454/4885MMP13 312/4885MMP1 643/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.