SCHEMBL598146

SCHEMBL598146

COc1ccc(S(=O)(=O)N(CC(=O)NO)CC(C)C)cc1

nearest known ligand 0.79

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MMP3 P08254 14/20 0.79
MMP13 P45452 5/20 0.78
MMP1 P03956 4/20 0.78
MMP8 P22894 4/20 0.78
MMP7 P09237 2/20 0.78
MMP12 P39900 2/20 0.78
MEP1B Q16820 2/20 0.71
BMP1 P13497 1/20 0.70
MMP2 P08253 3/20 0.69
MMP14 P50281 3/20 0.69
ADAMTS4 O75173 1/20 0.69
ADAMTS5 Q9UNA0 1/20 0.69
MMP9 P14780 2/20 0.69
ADAM17 P78536 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6418821 0.91 MMP13 (0.76) MMP3MMP13MMP1MMP8MMP7
SCHEMBL26776651 0.90 MMP13 (0.74) MMP3MMP13MMP1MMP8MMP7
SCHEMBL7350210 0.88 MMP3 (1.00) MMP3MMP13MMP1MMP8MMP7
SCHEMBL1566876 0.88 MMP13 (1.00) MMP3MMP13MMP1MMP8MMP7
SCHEMBL1566873 0.88 MMP13 (1.00) MMP3MMP13MMP1MMP8MMP7
SCHEMBL1566475 0.88 MMP13 (1.00) MMP3MMP13MMP1MMP8MMP7
SCHEMBL7348184 0.87 MMP3 (0.82) MMP3MMP13MMP1MMP8MMP7
SCHEMBL26776615 0.87 MMP3 (0.83) MMP3MMP13MMP1MMP8MMP7
SCHEMBL7346040 0.86 MMP3 (1.00) MMP3MMP13MMP1MMP8MMP7
SCHEMBL26781503 0.86 MMP3 (0.76) MMP3MMP13MMP1MMP8MMP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260009051-A1 COMPOSITIONS AND METHODS FOR ARTIFICIAL PROTOSPACER ADJACENT MOTIF (PAM) GENERATION VOR BIOPHARMA INC. (US) 2026-01-08 US claimed
EP-4555091-A2 COMPOSITIONS AND METHODS FOR ARTIFICIAL PROTOSPACER ADJACENT MOTIF (PAM) GENERATION Vor Biopharma Inc. (US) 2025-05-21 EP claimed
US-20250011425-A1 COMPOSITIONS AND METHODS FOR IMPROVED T CELLS UNIV TEMPLE (US) 2025-01-09 US claimed
US-12024715-B2 Compositions and methods for improved T cells TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2024-07-02 US claimed
WO-2024015925-A2 COMPOSITIONS AND METHODS FOR ARTIFICIAL PROTOSPACER ADJACENT MOTIF (PAM) GENERATION VOR BIOPHARMA INC. (US) 2024-01-18 WO claimed
CN-111803646-B Solid tumor combination treatment composition 苏州大学 2022-07-05 CN claimed
US-20100119489-A1 Stimulation of Pancreatic Beta Cell Proliferation STOFFEL MARKUS 2010-05-13 US claimed
EP-1896605-A2 STIMULATION OF PANCREATIC B CELL PROLIFERATION The Rockefeller University (US) 2008-03-12 EP claimed
WO-2006133333-A2 STIMULATION OF PANCREATIC B CELL PROLIFERATION THE ROCKEFELLER UNIVERSITY (US) 2006-12-14 WO claimed
WO-2026107352-A1 COMPOSITIONS AND METHODS FOR EFFICIENT NUCLEIC ACID ASSEMBLY AND TISSUE ENGINEERING PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2026-05-21 WO disclosed
US-20260061086-A1 COMPOUNDS COMPRISING A FIBROBLAST ACTIVATION PROTEIN LIGAND AND USE THEREOF 3B PHARMACEUTICALS GMBH (DE) 2026-03-05 US disclosed
US-20260009051-A1 COMPOSITIONS AND METHODS FOR ARTIFICIAL PROTOSPACER ADJACENT MOTIF (PAM) GENERATION VOR BIOPHARMA INC. (US) 2026-01-08 US disclosed
WO-2025226325-A2 IN VITRO SYSTEMS FOR GENERATION OF SKIN EQUIVALENTS AND USES THEREOF AND METHODS FOR DIAGNOSIS AND TREATMENT OF CONNECTIVE TISSUE DISORDERS THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2025-10-30 WO disclosed
US-12427210-B2 Compounds comprising a fibroblast activation protein ligand and use thereof 3B PHARMACEUTICALS GMBH (DE) 2025-09-30 US disclosed
US-5646167-A ADMINISTERED AS METALLOPROTEINASE INHIBITOR, ANTITUMOR OR ANTICARCINOGENIC AGENT CIBA-GEIGY CORPORATION (US) 1997-07-08 US disclosed
WO-1996040101-A1 CERTAIN ARYLSULFONAMIDO-SUBSTITUTED HYDROXAMIC ACIDS FOR THE TREATMENT OF CERTAIN TUMORS NOVARTIS AG (CH) 1996-12-19 WO disclosed
US-5552419-A METALLOPROTEINASE INHIBITORS CIBA-GEIGY CORPORATION (US) 1996-09-03 US disclosed
US-5506242-A METALLOELASTASE INHIBITOR; TREATS EMPHYSEMA CIBA-GEIGY CORPORATION (US) 1996-04-09 US disclosed
US-5455258-A Useful as inhibitors of matrix-degrading metalloproteinase enzymes such as stromelysin and/or collegenase CIBA-GEIGY CORPORATION (US) 1995-10-03 US disclosed
EP-0606046-A1 Arylsulfonamido-substituted hydroxamic acids CIBA-GEIGY AG (CH) 1994-07-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260061086-A1 COMPOUNDS COMPRISING A FIBROBLAST ACTIVATION PROTEIN LIGAND AND USE THEREOF FAP, FIBP, FGF23 MMP3 390/4885MMP13 377/4885MMP1 182/4885
US-12427210-B2 Compounds comprising a fibroblast activation protein ligand and use thereof FIBP, FGF2, FRS2 MMP3 533/4885MMP13 347/4885MMP1 234/4885
US-20260009051-A1 COMPOSITIONS AND METHODS FOR ARTIFICIAL PROTOSPACER ADJACENT MOTIF (PAM) GENERATION ZFR, DCLRE1B, ZFX MMP3 3782/4885MMP13 3723/4885MMP1 4359/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.