Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.62 |
| ▸ | PKLR | P30613 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | CDK5 | Q00535 | 6/20 | 0.50 |
| ▸ | CDK5R1 | Q15078 | 5/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.50 |
| ▸ | GSK3A | P49840 | 2/20 | 0.50 |
| ▸ | GSK3B | P49841 | 2/20 | 0.50 |
| ▸ | TOP1 | P11387 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 3/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.46 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26773449 | 0.82 | F2 (0.54) | NPSR1RXFP1MAPTKDM4EALDH1A1 | |
| SCHEMBL26773453 | 0.78 | PDE2A (0.59) | PDE2APKLRNPSR1RXFP1CDK5 | |
| SCHEMBL29368885 | 0.78 | PDE2A (1.00) | PDE2APKLRNPSR1RXFP1MAPT | |
| SCHEMBL803408 | 0.78 | PDE2A (1.00) | PDE2APKLRNPSR1RXFP1MAPT | |
| SCHEMBL29401099 | 0.78 | PDE2A (1.00) | PDE2APKLRNPSR1RXFP1MAPT | |
| SCHEMBL26773292 | 0.77 | PDE2A (0.57) | PDE2APKLRNPSR1RXFP1CDK5 | |
| SCHEMBL1668291 | 0.75 | F2 (0.56) | PDE2ACDK5CDK5R1DYRK1AGSK3A | |
| SCHEMBL30863879 | 0.74 | NOS1 (0.61) | NPSR1CDK5CDK5R1DYRK1AGSK3A | |
| SCHEMBL241569 | 0.74 | NOS1 (0.61) | NPSR1CDK5CDK5R1DYRK1AGSK3A | |
| SCHEMBL30282769 | 0.74 | NOS1 (0.61) | NPSR1CDK5CDK5R1DYRK1AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11820751-B2 | Urolithin derivatives and methods of use thereof | VANDRIA SA (CH) | 2023-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11820751-B2 | Urolithin derivatives and methods of use thereof | NLN, UQCRC2, TUFM | PDE2A 1089/4885PKLR 1783/4885NPSR1 3213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.