Sugi Predict

Sugi Predict / Compounds / SCHEMBL241569

SCHEMBL241569

SCHEMBL241569

O=c1[nH]c2ccc(O)cc2o1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NOS1 P29475 4/20 0.61
▸ KDM4E B2RXH2 3/20 0.54
▸ ALDH1A1 P00352 3/20 0.54
▸ CREBBP Q92793 1/20 0.54
▸ OGT O15294 1/20 0.53
▸ PDE3B Q13370 1/20 0.53
▸ PDE3A Q14432 1/20 0.53
▸ KMO O15229 1/20 0.50
▸ CDK5 Q00535 3/20 0.47
▸ CDK5R1 Q15078 3/20 0.47
▸ DYRK1A Q13627 2/20 0.47
▸ TOP1 P11387 1/20 0.47
▸ GSK3A P49840 1/20 0.47
▸ GSK3B P49841 1/20 0.47
▸ NOS3 P29474 3/20 0.47
▸ NOS2 P35228 3/20 0.47
▸ LMNA P02545 2/20 0.47
▸ CYP1A2 P05177 1/20 0.47
▸ ADRA2A P08913 1/20 0.47
▸ TSHR P16473 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30863879 1.00 NOS1 (0.61) NOS1KDM4EALDH1A1CREBBPOGT
SCHEMBL30282769 0.84 NOS1 (0.61) NOS1KDM4EALDH1A1CREBBPOGT
SCHEMBL240915 0.84 NOS1 (0.61) NOS1KDM4EALDH1A1CREBBPOGT
Formic Acid SCHEMBL31731276 0.78 NOS1 (0.54) NOS1KDM4EALDH1A1CREBBPOGT
SCHEMBL1668291 0.77 F2 (0.56) CDK5CDK5R1DYRK1ATOP1GSK3A
SCHEMBL25394296 0.77 KDM4E (0.55) KDM4EALDH1A1CDK5CDK5R1DYRK1A
SCHEMBL2058961 0.76 NOS1 (0.61) NOS1KDM4EALDH1A1CREBBPOGT
SCHEMBL993598 0.76 NOS1 (0.61) NOS1KDM4EALDH1A1CREBBPOGT
SCHEMBL8131111 0.76 NOS1 (0.61) NOS1KDM4EALDH1A1CREBBPOGT
SCHEMBL244119 0.76 NOS1 (1.00) NOS1KDM4EALDH1A1CREBBPOGT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0026474-B1 COMPOSITION AND PROCESS FOR OXIDATIVE DYEING OF HAIR Wella Aktiengesellschaft (DE) 1983-06-08 — — EP claimed
EP-0026474-A1 Composition and process for oxidative dyeing of hair Wella Aktiengesellschaft (DE) 1981-04-08 — — EP claimed
WO-1981000811-A1 MEANS AND PROCESS ALLOWING HAIR COLORATION BY OXIDATION WELLA AG (DE) 1981-04-02 — — WO claimed
US-20250127903-A1 SUBSTITUTED PIPERIDINE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION C4 THERAPEUTICS, INC. (US) 2025-04-24 — — US disclosed
US-11584717-B2 MIF modulators YALE UNIVERSITY (US) 2023-02-21 — — US disclosed
US-20220162161-A1 Novel compounds and their uses as thyroid hormone receptor agonists NANJING RUIJIE PHARMA CO., LTD. (CN) 2022-05-26 — — US disclosed
EP-2170334-B1 NMDA RECEPTOR ANTAGONISTS FOR NEUROPROTECTION UNIV EMORY (US) 2021-03-17 — — EP disclosed
US-20200377457-A1 MIF MODULATORS UNIV YALE (US) 2020-12-03 — — US disclosed
US-20200377457-A1 MIF MODULATORS UNIV YALE (US) 2020-12-03 — — US disclosed
US-20190270706-A1 MIF MODULATORS UNIV YALE (US) 2019-09-05 — — US disclosed
EP-3455219-A1 AMINE-LINKED C3-GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION C4 Therapeutics, Inc. (US) 2019-03-20 — — EP disclosed
US-20090253710-A1 NMDA Receptor Antagonists for Neuroprotection EMORY UNIVERSITY 2009-10-08 — — US disclosed
US-20090253710-A1 NMDA Receptor Antagonists for Neuroprotection EMORY UNIVERSITY 2009-10-08 — — US disclosed
US-20090253710-A1 NMDA Receptor Antagonists for Neuroprotection EMORY UNIVERSITY 2009-10-08 — — US disclosed
WO-2009006437-A1 NMDA RECEPTOR ANTAGONISTS FOR NEUROPROTECTION EMORY UNIVERSITY (US) 2009-01-08 — — WO disclosed
WO-2009006437-A1 NMDA RECEPTOR ANTAGONISTS FOR NEUROPROTECTION EMORY UNIVERSITY (US) 2009-01-08 — — WO disclosed
US-7202251-B2 Bicyclic anilide spirohydantoin CGRP receptor antagonists MERCK & CO., INC. (US) 2007-04-10 — — US disclosed
US-7202251-B2 Bicyclic anilide spirohydantoin CGRP receptor antagonists MERCK & CO., INC. (US) 2007-04-10 — — US disclosed
US-4620850-A HYDROXYBENZOLFURANONE WELLA AKTIENGESELLSCHAFT (DE) 1986-11-04 — — US disclosed
EP-0026474-B1 COMPOSITION AND PROCESS FOR OXIDATIVE DYEING OF HAIR Wella Aktiengesellschaft (DE) 1983-06-08 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11584717-B2 MIF modulators MIF, HMGB2, HMGB3 NOS1 492/4885KDM4E 3588/4885ALDH1A1 584/4885
US-20220162161-A1 Novel compounds and their uses as thyroid hormone receptor agonists THRA, THRB, TSHR NOS1 1489/4885KDM4E 3994/4885ALDH1A1 2389/4885
US-20200377457-A1 MIF MODULATORS MIF, HMGB2, HMGB3 NOS1 492/4885KDM4E 3588/4885ALDH1A1 584/4885
US-20090253710-A1 NMDA Receptor Antagonists for Neuroprotection GRIN1, GRIN2C, GRIK1 NOS1 3435/4885KDM4E 2576/4885ALDH1A1 2664/4885
US-20250127903-A1 SUBSTITUTED PIPERIDINE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION STUB1, UBE3C, NEDD4 NOS1 4803/4885KDM4E 775/4885ALDH1A1 2429/4885
US-20190270706-A1 MIF MODULATORS MIF, HMGB2, HMGB3 NOS1 492/4885KDM4E 3588/4885ALDH1A1 584/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.