SCHEMBL2677427

SCHEMBL2677427

CCCOC(=O)/N=N/C(=O)OCCC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.43
ALDH1A1 P00352 8/20 0.41
LMNA P02545 2/20 0.40
TSHR P16473 2/20 0.39
ESR1 P03372 1/20 0.39
CHRM1 P11229 1/20 0.39
SLC6A2 P23975 1/20 0.39
KDR P35968 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ATM Q13315 1/20 0.36
NAAA Q02083 1/20 0.34
DGKA P23743 1/20 0.34
KDM4E B2RXH2 1/20 0.34
GLA P06280 1/20 0.34
HPGD P15428 1/20 0.33
PPM1B O75688 1/20 0.33
PTPN1 P18031 1/20 0.33
ACHE P22303 1/20 0.33
HSD17B10 Q99714 1/20 0.33
PPP1CC P36873 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1679083 1.00 HCAR2 (0.43) HCAR2ALDH1A1LMNATSHRESR1
SCHEMBL15842890 0.93 ALDH1A1 (0.42) HCAR2ALDH1A1LMNATSHRESR1
SCHEMBL15842891 0.93 ALDH1A1 (0.42) HCAR2ALDH1A1LMNATSHRESR1
SCHEMBL15843352 0.91 ALDH1A1 (0.54) HCAR2ALDH1A1LMNATSHRESR1
SCHEMBL15843351 0.91 ALDH1A1 (0.54) HCAR2ALDH1A1LMNATSHRESR1
SCHEMBL121367 0.91 HCAR2 (0.42) HCAR2ALDH1A1LMNATSHRESR1
SCHEMBL15843771 0.91 HCAR2 (0.38) HCAR2ALDH1A1LMNATSHRESR1
SCHEMBL14723127 0.91 HCAR2 (0.42) HCAR2ALDH1A1LMNATSHRESR1
SCHEMBL15843772 0.91 HCAR2 (0.38) HCAR2ALDH1A1LMNATSHRESR1
SCHEMBL15843113 0.89 NAAA (0.52) HCAR2ALDH1A1LMNATSHRATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115947675-B Rasagiline intermediate and preparation method and application thereof 博济医药科技股份有限公司 2024-05-31 CN claimed
CN-115947675-A Rasagiline intermediate and preparation method and application thereof 博济医药科技股份有限公司 2023-04-11 CN claimed
CN-114560901-A Preparation method of ergosterol or derivative thereof 湖南醇康医药科技有限公司 2022-05-31 CN claimed
EP-3938374-A2 PHENYLPROPANOID SACCHARIDE ESTERS, METHODS AND USES THEREOF UNIVERSIDADE NOVA DE LISBOA (PT) 2022-01-19 EP claimed
WO-2020183442-A2 PHENYLPROPANOID SACCHARIDE ESTERS, METHODS AND USES THEREOF UNIVERSIDADE NOVA DE LISBOA (PT) 2020-09-17 WO claimed
US-9315599-B2 Functionalized polymers BRIDGESTONE CORPORATION (JP) 2016-04-19 US claimed
US-20160083373-A1 METHOD FOR PREPARING AFATINIB AND INTERMEDIATE THEREOF SUZHOU MIRACPHARMA TECHNOLOGY CO., LTD. (CN) 2016-03-24 US claimed
WO-2014107447-A1 FUNCTIONALIZED POLYMERS BRIDGESTONE CORPORATION (JP) 2014-07-10 WO claimed
US-20140187712-A1 FUNCTIONALIZED POLYMERS BRIDGESTONE CORPORATION (JP) 2014-07-03 US claimed
CN-114560901-B Preparation method of ergosterol or derivative thereof 湖南龙腾生物科技有限公司 2024-07-05 CN disclosed
CN-115947675-B Rasagiline intermediate and preparation method and application thereof 博济医药科技股份有限公司 2024-05-31 CN disclosed
EP-3868766-B1 PHOTOLUMINESCENT GREASE COMPOSITION, PHOTOLUMINESCENT MATERIAL AND PREPARATION METHOD THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2024-05-08 EP disclosed
CN-113387844-B Preparation method of dialkyl azodicarbonate 浙江瑞博制药有限公司 2024-03-12 CN disclosed
US-11898118-B2 Photoluminescent lubricating grease composition, photoluminescent material and the preparation methods thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2024-02-13 US disclosed
EP-0335355-A2 Bis-(hydroxymethyl) cyclobutyl purines and pyrimidines E.R. Squibb & Sons, Inc. (US) 1989-10-04 EP disclosed
US-4820815-A USEFUL AS ANTIBACTERIALS OR TO FORM FUSED BICYCLIC B-LACTAM ANTIBIOTICS LIKE CARBAPENEMS UNIVERSITY OF NOTRE DAME DU LAC (US) 1989-04-11 US disclosed
EP-0306266-A1 Azetidinone n-phosphonomethyl esters THE UNIVERSITY OF NOTRE DAME DU LAC (US) 1989-03-08 EP disclosed
EP-0136779-B1 NEW CARBACYCLIN DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM SANKYO COMPANY LIMITED (JP) 1988-09-14 EP disclosed
EP-0136779-A1 New carbacyclin derivatives, processes for their preparation and compositions containing them SANKYO COMPANY LIMITED (JP) 1985-04-10 EP disclosed
US-3994941-A METHYLOLATION, PHTHALIMIDATION THE UPJOHN COMPANY (US) 1976-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11898118-B2 Photoluminescent lubricating grease composition, photoluminescent material and the preparation methods thereof TPSD1, TPSG1, TPSB2 HCAR2 4660/4885ALDH1A1 793/4885LMNA 1410/4885
US-20160083373-A1 METHOD FOR PREPARING AFATINIB AND INTERMEDIATE THEREOF ABL1, CDK4, ERBB2 HCAR2 4001/4885ALDH1A1 463/4885LMNA 963/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.