Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA7 | P43166 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | DTYMK | P23919 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL267752 | 0.85 | DTYMK (0.64) | TSHRCA1CA2CA12CA7 | |
| SCHEMBL28134449 | 0.85 | DTYMK (0.64) | TSHRCA1CA2CA12CA7 | |
| SCHEMBL31283743 | 0.85 | DTYMK (0.64) | TSHRCA1CA2CA12CA7 | |
| SCHEMBL6397073 | 0.83 | DTYMK (0.62) | TSHRCA1CA2CA12CA7 | |
| SCHEMBL1663487 | 0.83 | KCNMA1 (0.47) | TSHRALDH1A1CYP3A4ALOX15BACE1 | |
| SCHEMBL2327506 | 0.83 | BACE1 (0.45) | ALDH1A1CYP3A4BACE1NPSR1RXFP1 | |
| SCHEMBL10831554 | 0.83 | DTYMK (0.62) | TSHRCA1CA2CA12CA7 | |
| SCHEMBL1883040 | 0.83 | MAPT (0.49) | TSHRALDH1A1CYP3A4ALOX15BACE1 | |
| SCHEMBL8375405 | 0.82 | TDP1 (0.52) | TSHRALDH1A1DTYMKCYP3A4ALOX15 | |
| SCHEMBL145092 | 0.81 | CASP6 (0.72) | TSHRCASP6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184679-A | Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material | 中国石油天然气股份有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-115011025-B | Overhead insulated conductor with corrosion-resistant shell and preparation method thereof | 任丘市嘉华电讯器材有限公司 | 2023-05-09 | — | — | CN | claimed |
| CN-115011025-A | Overhead insulated conductor with corrosion-resistant shell and preparation method thereof | 任丘市嘉华电讯器材有限公司 | 2022-09-06 | — | — | CN | claimed |
| CN-113214714-A | High-molecular coating for medical instrument with barrier biological film and preparation method thereof | 金赛花 | 2021-08-06 | — | — | CN | claimed |
| CN-112281492-A | Anti-aging textile fabric and preparation method thereof | 玉环德谷新材料科技有限公司 | 2021-01-29 | — | — | CN | claimed |
| US-10626141-B2 | Method for specific cleavage of C alpha-C bond and side chain of protein and peptide, and method for determining amino acid sequence | SHIMADZU CORPORATION (JP) | 2020-04-21 | — | — | US | claimed |
| EP-3246706-A1 | METHOD FOR SPECIFIC CLEAVAGE OF C(ALPHA)-C BOND AND SIDE CHAIN OF PROTEIN AND PEPTIDE, AND METHOD FOR DETERMINING AMINO ACID SEQUENCE | Shimadzu Corporation (JP) | 2017-11-22 | — | — | EP | claimed |
| US-20170327533-A1 | METHOD FOR SPECIFIC CLEAVAGE OF C Alpha-C BOND AND SIDE CHAIN OF PROTEIN AND PEPTIDE, AND METHOD FOR DETERMINING AMINO ACID SEQUENCE | SHIMADZU CORPORATION (JP) | 2017-11-16 | — | — | US | claimed |
| EP-0206635-B1 | PREPARATION OF 3-AMINO-4-HYDROXYBENZOIC ACIDS | THE DOW CHEMICAL COMPANY (US) | 1989-11-15 | — | — | EP | claimed |
| CN-119060060-A | Imidazole-containing ALK2 kinase inhibitors | 拜奥克里斯特制药公司 | 2024-12-03 | — | — | CN | disclosed |
| US-20240376117-A1 | IMIDAZOLE-CONTAINING INHIBITORS OF ALK2 KINASE | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2024-11-14 | — | — | US | disclosed |
| CN-110913855-B | Imidazole-containing ALK2 kinase inhibitors | 拜奥克里斯特制药公司 | 2024-09-03 | — | — | CN | disclosed |
| US-12054492-B2 | Imidazole-containing inhibitors of ALK2 kinase | BIOCRYST PHARMACEUTICALS, INC. (US) | 2024-08-06 | — | — | US | disclosed |
| CN-118184679-A | Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material | 中国石油天然气股份有限公司 | 2024-06-14 | — | — | CN | disclosed |
| US-4849010-A | Herbicidal sulfonamides | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1989-07-18 | — | — | US | disclosed |
| EP-0284174-A1 | Therapeutic preparations | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-09-28 | — | — | EP | disclosed |
| US-4724039-A | RICE CROP | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-02-09 | — | — | US | disclosed |
| US-4710221-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-12-01 | — | — | US | disclosed |
| EP-0235449-A1 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-09-09 | — | — | EP | disclosed |
| EP-0162723-A2 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-11-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170327533-A1 | METHOD FOR SPECIFIC CLEAVAGE OF C Alpha-C BOND AND SIDE CHAIN OF PROTEIN AND PEPTIDE, AND METHOD FOR DETERMINING AMINO ACID SEQUENCE | CPN1, CYBA, CRYAB | TSHR 4102/4885CA1 115/4885CA2 110/4885 |
| US-10626141-B2 | Method for specific cleavage of C alpha-C bond and side chain of protein and peptide, and method for determining amino acid sequence | CPN1, CYBA, CRYAB | TSHR 4102/4885CA1 115/4885CA2 110/4885 |
| US-20240376117-A1 | IMIDAZOLE-CONTAINING INHIBITORS OF ALK2 KINASE | ALK, ACVR2B, ACVR2A | TSHR 3668/4885CA1 4274/4885CA2 340/4885 |
| US-12054492-B2 | Imidazole-containing inhibitors of ALK2 kinase | ALK, ACVR2B, ACVR2A | TSHR 3668/4885CA1 4274/4885CA2 340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.