Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.36 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.36 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.36 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.36 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.35 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL706579 | 0.88 | TDP1 (0.41) | TDP1SLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL26780258 | 0.88 | TDP1 (0.41) | TDP1SLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL16594630 | 0.85 | SLC28A1 (0.46) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL16863925 | 0.79 | TDP1 (0.34) | TDP1SLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL1318516 | 0.78 | TDP1 (0.41) | TDP1SLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL12458446 | 0.78 | TDP1 (0.36) | TDP1SLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL9964294 | 0.78 | TDP1 (0.36) | TDP1SLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL25504782 | 0.77 | SLC28A1 (0.34) | TDP1SLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL9893207 | 0.77 | SLC28A1 (0.34) | TDP1SLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL1317537 | 0.75 | TDP1 (0.36) | TDP1SLC28A1SLC28A2SLC29A1SLC28A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841401-B1 | METHOD FOR PROTECTING HYDROXYL, AMINE OR THIOL FUNCTIONAL GROUPS WITH TETRAISOPROPYLDISILANE AND THE CORRESPONDING PROTECTED COMPOUNDS | INST CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK (PL) | 2018-07-04 | — | — | EP | disclosed |
| US-9290521-B2 | Method for protecting hydroxyl or amine or thiol functions, novel compounds with protected hydroxyl or amine or thiol groups, as well novel compounds for the implementation of this method | INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK (PL) | 2016-03-22 | — | — | US | disclosed |
| US-20150094462-A1 | METHOD FOR PROTECTING HYDROXYL OR AMINE OR THIOL FUNCTIONS, NOVEL COMPOUNDS WITH PROTECTED HYDROXYL OR AMINE OR THIOL GROUPS, AS WELL NOVEL COMPOUNDS FOR THE IMPLEMENTATION OF THIS METHOD | FUNDACJA UNIWERSYTETU IM. ADAMA MICKIEWICZA W POZNANIU (PL) | 2015-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150094462-A1 | METHOD FOR PROTECTING HYDROXYL OR AMINE OR THIOL FUNCTIONS, NOVEL COMPOUNDS WITH PROTECTED HYDROXYL OR AMINE OR THIOL GROUPS, AS WELL NOVEL COMPOUNDS FOR THE IMPLEMENTATION OF THIS METHOD | DUS2, TXN, OGG1 | TDP1 166/4885SLC28A1 150/4885SLC28A2 167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.