SCHEMBL26787128

SCHEMBL26787128

CC(C)c1c2ccc(N(C)C)cc2nc2cc(N(C)C)ccc12

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ APP P05067 2/20 0.57
▸ TERT O14746 2/20 0.57
▸ ELANE P08246 2/20 0.49
▸ APAF1 O14727 1/20 0.44
▸ EGFR P00533 2/20 0.42
▸ KDM1A O60341 6/20 0.39
▸ PDE3B Q13370 1/20 0.38
▸ PDE3A Q14432 1/20 0.38
▸ KDM4E B2RXH2 1/20 0.38
▸ PSMB5 P28074 1/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ ALOX15 P16050 1/20 0.36
▸ TSHR P16473 1/20 0.36
▸ HSD17B10 Q99714 1/20 0.36
▸ IP6K1 Q92551 1/20 0.36
▸ PARP14 Q460N5 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24299673 0.79 APP (0.63) APPTERTELANEAPAF1EGFR
Acridine Orange SCHEMBL29361720 0.73 TERT (1.00) APPTERTELANEAPAF1EGFR
Acridine Orange SCHEMBL297155 0.73 TERT (1.00) APPTERTELANEAPAF1EGFR
SCHEMBL11443324 0.73 APP (0.74) APPTERTAPAF1EGFRPDE3B
SCHEMBL5696512 0.73 APP (0.74) APPTERTAPAF1EGFRPDE3B
Acridine Orange SCHEMBL20816123 0.71 TERT (0.95) APPTERTELANEAPAF1EGFR
Acridine Orange SCHEMBL22071 0.71 TERT (0.95) APPTERTELANEAPAF1EGFR
Hydrochloric Acid SCHEMBL2478442 0.71 APP (0.71) APPTERTAPAF1EGFRPDE3B
Acridine Orange SCHEMBL30153753 0.71 TERT (0.95) APPTERTELANEAPAF1EGFR
Acridine Orange SCHEMBL29597528 0.71 TERT (0.95) APPTERTELANEAPAF1EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230366045-A1 NUCLEIC ACID CROSSLINKING REAGENTS AND USES THEREOF PROMEGA CORPORATION 2023-11-16 — — US disclosed
US-20230366045-A1 NUCLEIC ACID CROSSLINKING REAGENTS AND USES THEREOF PROMEGA CORPORATION 2023-11-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230366045-A1 NUCLEIC ACID CROSSLINKING REAGENTS AND USES THEREOF POLM, HNRNPM, POLRMT APP 3504/4885TERT 440/4885ELANE 1024/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback